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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 16.36
Human Site: T279 Identified Species: 22.5
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 T279 S A S S R Q E T T D S K S S L
Chimpanzee Pan troglodytes XP_526227 1093 122795 T279 S A S S R Q E T T D S K S S L
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 T278 S A S S R Q E T T D S K S S L
Dog Lupus familis XP_533766 1089 122761 D277 S S R Q E T T D S K S S L H L
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 D277 S S R Q E T S D A K S S L H L
Rat Rattus norvegicus NP_446123 1093 121882 D278 S S R Q E T S D A K S S L H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 A285 S A S S R Q E A A D S K S S L
Chicken Gallus gallus O42184 1433 161009 A377 A E R D L E R A E V A K A T S
Frog Xenopus laevis Q5PQ23 649 75475
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 T305 S A S S R Q E T A E A K A G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 K229 L Q M S H K G K S P A P A K T
Honey Bee Apis mellifera XP_394037 1326 150590 D318 S S V E V L G D W K S D T S P
Nematode Worm Caenorhab. elegans P02566 1966 225108 L910 L E S T K T Q L S D A E E R L
Sea Urchin Strong. purpuratus XP_785821 1176 131318 Q284 E N D T L V D Q P L G Q S L E
Poplar Tree Populus trichocarpa XP_002303293 975 109171 S272 A G A V L D S S S S Q P V S A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 S253 N L E G R T S S K N F E V S P
Baker's Yeast Sacchar. cerevisiae P47166 707 81153
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 100 100 20 N.A. 20 20 N.A. 86.6 6.6 0 66.6 N.A. 6.6 20 20 6.6
P-Site Similarity: 100 100 100 33.3 N.A. 26.6 26.6 N.A. 86.6 40 0 86.6 N.A. 33.3 33.3 60 26.6
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 0 N.A.
P-Site Similarity: 33.3 N.A. N.A. 40 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 30 6 0 0 0 0 12 24 0 24 0 18 0 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 6 6 0 6 6 24 0 30 0 6 0 0 0 % D
% Glu: 6 12 6 6 18 6 30 0 6 6 0 12 6 0 6 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % F
% Gly: 0 6 0 6 0 0 12 0 0 0 6 0 0 6 0 % G
% His: 0 0 0 0 6 0 0 0 0 0 0 0 0 18 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 6 6 0 6 6 24 0 36 0 6 0 % K
% Leu: 12 6 0 0 18 6 0 6 0 6 0 0 18 6 53 % L
% Met: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 6 0 0 0 0 0 0 0 6 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 6 6 0 12 0 0 12 % P
% Gln: 0 6 0 18 0 30 6 6 0 0 6 6 0 0 0 % Q
% Arg: 0 0 24 0 36 0 6 0 0 0 0 0 0 6 0 % R
% Ser: 53 24 36 36 0 0 24 12 24 6 48 18 30 42 6 % S
% Thr: 0 0 0 12 0 30 6 24 18 0 0 0 6 6 6 % T
% Val: 0 0 6 6 6 6 0 0 0 6 0 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _